Topoisomerase IIIalpha is required for normal proliferation and telomere stability in alternative le...
Topoisomerase IIIalpha is required for normal proliferation and telomere stability in alternative lengthening of telomeres
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England
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Language
English
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England
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Topoisomerase (Topo) IIIalpha associates with BLM helicase, which is proposed to be important in the alternative lengthening of telomeres (ALT) pathway that allows telomere recombination in the absence of telomerase. Here, we show that human Topo IIIalpha colocalizes with telomeric proteins at ALT-associated promyelocytic bodies from ALT cells. In...
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Topoisomerase IIIalpha is required for normal proliferation and telomere stability in alternative lengthening of telomeres
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TN_cdi_proquest_miscellaneous_70761718
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70761718
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E-ISSN
1460-2075
DOI
10.1038/emboj.2008.74
