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Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures

Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70778359

Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures

About this item

Full title

Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures

Publisher

London: Nature Publishing Group UK

Journal title

Nature, 2008-05, Vol.453 (7194), p.489-494

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The RecA family of ATPases mediates homologous recombination, a reaction essential for maintaining genomic integrity and for generating genetic diversity. RecA, ATP and single-stranded DNA (ssDNA) form a helical filament that binds to double-stranded DNA (dsDNA), searches for homology, and then catalyses the exchange of the complementary strand, pr...

Alternative Titles

Full title

Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70778359

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70778359

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687,1476-4679

DOI

10.1038/nature06971

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