Interaction of Systemically Delivered Adenovirus Vectors with Kupffer Cells in Mouse Liver
Interaction of Systemically Delivered Adenovirus Vectors with Kupffer Cells in Mouse Liver
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Author / Creator
Publisher
Larchmont, NY: Liebert
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Language
English
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Publisher
Larchmont, NY: Liebert
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Scope and Contents
Contents
When adenovirus (Ad) vectors are injected intravenously they are rapidly taken up by Kupffer cells (KCs) in the liver. This results in massive KC necrosis within minutes, followed by a more gradual disappearance of KCs from the liver. It is not known how KCs recognize Ad, or why Ad kills KCs. We used a variety of mutated and fiber-pseudotyped Ad ve...
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Full title
Interaction of Systemically Delivered Adenovirus Vectors with Kupffer Cells in Mouse Liver
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TN_cdi_proquest_miscellaneous_70793949
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70793949
Other Identifiers
ISSN
1043-0342
E-ISSN
1557-7422
DOI
10.1089/hum.2008.004
