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Aberrant CpG-island methylation has non-random and tumour-type–specific patterns

Aberrant CpG-island methylation has non-random and tumour-type–specific patterns

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70887754

Aberrant CpG-island methylation has non-random and tumour-type–specific patterns

About this item

Full title

Aberrant CpG-island methylation has non-random and tumour-type–specific patterns

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2000-02, Vol.24 (2), p.132-138

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

CpG islands frequently contain gene promoters or exons
1
and are usually unmethylated in normal cells
1
,
2
,
3
. Methylation of CpG islands is associated with delayed replication, condensed chromatin and inhibition of transcription initiation
4
,
5
,
6
,
7
. The investigation of aberrant CpG-island m...

Alternative Titles

Full title

Aberrant CpG-island methylation has non-random and tumour-type–specific patterns

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70887754

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70887754

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/72785

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