Effect of P-glycoprotein modulation with cyclosporin A on cerebrospinal fluid penetration of doxorub...
Effect of P-glycoprotein modulation with cyclosporin A on cerebrospinal fluid penetration of doxorubicin in non-human primates
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Publisher
Berlin: Springer
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Language
English
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Publisher
Berlin: Springer
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Contents
P-glycoprotein (Pgp) is a transmembrane drug efflux pump that is expressed in multidrug-resistant cancer cells and in a variety of normal tissues, including brain capillary endothelial cells which comprise the blood-brain barrier. We studied the effects of the Pgp inhibitor, cyclosporin A (CsA), on the cerebrospinal fluid (CSF) penetration of the P...
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Full title
Effect of P-glycoprotein modulation with cyclosporin A on cerebrospinal fluid penetration of doxorubicin in non-human primates
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TN_cdi_proquest_miscellaneous_70898780
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70898780
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ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s002800050031
