Structure-based 3D QSAR and design of novel acetylcholinesterase inhibitors
Structure-based 3D QSAR and design of novel acetylcholinesterase inhibitors
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Author / Creator
Sippl, W , Contreras, J M , Parrot, I , Rival, Y M and Wermuth, C G
Publisher
Netherlands: Springer Nature B.V
Journal title
Language
English
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Publisher
Netherlands: Springer Nature B.V
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Scope and Contents
Contents
The paper describes the construction, validation and application of a structure-based 3D QSAR model of novel acetylcholinesterase (AChE) inhibitors. Initial use was made of four X-ray structures of AChE complexed with small, non-specific inhibitors to create a model of the binding of recently developed aminopyridazine derivatives. Combined automate...
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Full title
Structure-based 3D QSAR and design of novel acetylcholinesterase inhibitors
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_70908911
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70908911
Other Identifiers
ISSN
0920-654X
E-ISSN
1573-4951
DOI
10.1023/A:1011150215288
