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Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and...

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70945103

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

About this item

Full title

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

Publisher

Basingstoke: Nature Publishing

Journal title

Oncogene, 2000-02, Vol.19 (5), p.649-660

Language

English

Formats

Publication information

Publisher

Basingstoke: Nature Publishing

More information

Scope and Contents

Contents

The mechanisms by which the p53 tumour suppressor protein would, in vivo, co-ordinate the adaptive response to genotoxic stress is poorly understood. p53 has been shown to transactivate several genes that could be involved in two main cellular responses, growth arrest and apoptosis. To get further insight into the tissue-specific regulation of p53...

Alternative Titles

Full title

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70945103

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70945103

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1203366

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