Mutations truncating the EP300 acetylase in human cancers
Mutations truncating the EP300 acetylase in human cancers
About this item
Full title
Mutations truncating the EP300 acetylase in human cancers
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Nature genetics, 2000-03, Vol.24 (3), p.300-303
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The EP300 protein is a histone acetyltransferase
1
,
2
that regulates transcription via chromatin remodelling
3
and is important in the processes of cell proliferation
4
and differentiation
5
. EP300 acetylation of TP53 in response to DNA damage regulates its DNA-binding and transcription functions
6
,
7
,<...
Alternative Titles
Full title
Mutations truncating the EP300 acetylase in human cancers
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_70958055
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70958055
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/73536
