Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIG...
Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
LIGHT was recently described as a member of the tumor necrosis factor (TNF) ‘superfamily’. We have isolated a mouse homolog of human LIGHT and investigated its immunoregulatory functions
in vitro
and
in vivo
. LIGHT has potent, CD28-independent co-stimulatory activity leading to T-cell growth and secretion of gamma interferon and granul...
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Full title
Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway
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TN_cdi_proquest_miscellaneous_70973026
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70973026
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/73136
