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Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71038853

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13

About this item

Full title

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13

Publisher

New York: Nature Publishing Group US

Journal title

Nature Structural Biology, 2001-08, Vol.8 (8), p.669-673

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The ubiquitin conjugating enzyme complex Mms2–Ubc13 plays a key role in post-replicative DNA repair in yeast and the NF-κB signal transduction pathway in humans. This complex assembles novel polyubiquitin chains onto yet uncharacterized protein targets. Here we report the crystal structure of a complex between hMms2 (Uev1) and hUbc13 at 1.85 Å reso...

Alternative Titles

Full title

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71038853

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71038853

Other Identifiers

ISSN

1072-8368,1545-9993

E-ISSN

1545-9985

DOI

10.1038/90373

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