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Reversible ototoxic effect of azithromycin and clarithromycin on transiently evoked otoacoustic emis...

Reversible ototoxic effect of azithromycin and clarithromycin on transiently evoked otoacoustic emis...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71145912

Reversible ototoxic effect of azithromycin and clarithromycin on transiently evoked otoacoustic emissions in guinea pigs

About this item

Full title

Reversible ototoxic effect of azithromycin and clarithromycin on transiently evoked otoacoustic emissions in guinea pigs

Publisher

Cambridge, UK: Cambridge University Press

Journal title

Journal of laryngology and otology, 2001-08, Vol.115 (8), p.622-628

Language

English

Formats

Publication information

Publisher

Cambridge, UK: Cambridge University Press

More information

Scope and Contents

Contents

The possible cochlear toxicity of systemically applied macrolides - erythromycin (ER), azithromycin (AZ) and clarithromycin(CL) - was investigated in guinea pigs by measuring transiently evoked otoacoustic emissions (TEOAEs). A single dose of 125 mg/kg intravenous (i.v.) ER caused no change in TEOAEs in guinea pigs (p>0.05), whereas AZ (45 mg/kg or...

Alternative Titles

Full title

Reversible ototoxic effect of azithromycin and clarithromycin on transiently evoked otoacoustic emissions in guinea pigs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71145912

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71145912

Other Identifiers

ISSN

0022-2151

E-ISSN

1748-5460

DOI

10.1258/0022215011908676

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