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Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long...

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71158187

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells

About this item

Full title

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2000-06, Vol.6 (6), p.652-658

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Pre-clinical studies indicate that efficient retrovirus-mediated gene transfer into hematopoietic stem cells and progenitor cells can be achieved by co-localizing retroviral particles and target cells on specific adhesion domains of fibronectin. In this pilot study, we used this technique to transfer the human multidrug resistance 1 gene into stem...

Alternative Titles

Full title

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71158187

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71158187

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/76225

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