Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long...
Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells
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Author / Creator
Abonour, Rafat , Williams, David A. , Einhorn, Lawrence , Hall, Kristin M. , Chen, Jun , Coffman, John , Traycoff, Christie M. , Bank, Arthur , Kato, Ikunoshin , Ward, Maureen , Williams, Stephen D. , Hromas, Robert , Robertson, Michael J. , Smith, Franklin O. , Woo, David , Mills, Bonnie , Srour, Edward F. and Cornetta, Kenneth
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Pre-clinical studies indicate that efficient retrovirus-mediated gene transfer into hematopoietic stem cells and progenitor cells can be achieved by co-localizing retroviral particles and target cells on specific adhesion domains of fibronectin. In this pilot study, we used this technique to transfer the human multidrug resistance 1 gene into stem...
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Full title
Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells
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Record Identifier
TN_cdi_proquest_miscellaneous_71158187
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71158187
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/76225