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Genetic Characterization of Thymidine Kinase from Acyclovir-Resistant and -Susceptible Herpes Simple...

Genetic Characterization of Thymidine Kinase from Acyclovir-Resistant and -Susceptible Herpes Simple...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71232679

Genetic Characterization of Thymidine Kinase from Acyclovir-Resistant and -Susceptible Herpes Simplex Virus Type 1 Isolated from Bone Marrow Transplant Recipients

About this item

Full title

Genetic Characterization of Thymidine Kinase from Acyclovir-Resistant and -Susceptible Herpes Simplex Virus Type 1 Isolated from Bone Marrow Transplant Recipients

Publisher

Chicago, IL: The University of Chicago Press

Journal title

The Journal of infectious diseases, 2000-07, Vol.182 (1), p.290-293

Language

English

Formats

Publication information

Publisher

Chicago, IL: The University of Chicago Press

More information

Scope and Contents

Contents

Emergence of acyclovir (Acy)-resistant herpes simplex virus (HSV) is a major concern in bone marrow transplant recipients. Phenotypic and genetic characterization of thymidine kinase (TK) was done for 7 Acy-susceptible and 11 Acy-resistant HSV-1 isolated from 11 patients. In total, 19 amino acid substitutions were detected that were not related to...

Alternative Titles

Full title

Genetic Characterization of Thymidine Kinase from Acyclovir-Resistant and -Susceptible Herpes Simplex Virus Type 1 Isolated from Bone Marrow Transplant Recipients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71232679

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71232679

Other Identifiers

ISSN

0022-1899

E-ISSN

1537-6613

DOI

10.1086/315696

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