Soluble Adenylyl Cyclase as an Evolutionarily Conserved Bicarbonate Sensor
Soluble Adenylyl Cyclase as an Evolutionarily Conserved Bicarbonate Sensor
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Washington, DC: American Society for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Society for the Advancement of Science
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Contents
Spermatozoa undergo a poorly understood activation process induced by bicarbonate and mediated by cyclic adenosine 3′,5′-monophosphate (cAMP). It has been assumed that bicarbonate mediates its effects through changes in intracellular pH or membrane potential; however, we demonstrate here that bicarbonate directly stimulates mammalian soluble adenyl...
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Full title
Soluble Adenylyl Cyclase as an Evolutionarily Conserved Bicarbonate Sensor
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TN_cdi_proquest_miscellaneous_71270517
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71270517
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.289.5479.625
