Vivitrex®, an Injectable, Extended-Release Formulation of Naltrexone, Provides Pharmacokinetic and P...
Vivitrex®, an Injectable, Extended-Release Formulation of Naltrexone, Provides Pharmacokinetic and Pharmacodynamic Evidence of Efficacy for 1 Month in Rats
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Publisher
Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Contents
While oral naltrexone is effective in treating alcohol and opiate dependencies, poor patient adherence and widely fluctuating plasma levels limit its efficacy. To overcome these problems, an extended-release formulation of naltrexone (Vivitrex
®
) was developed by encapsulating naltrexone into injectable, biodegradable polymer microspheres. P...
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Full title
Vivitrex®, an Injectable, Extended-Release Formulation of Naltrexone, Provides Pharmacokinetic and Pharmacodynamic Evidence of Efficacy for 1 Month in Rats
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TN_cdi_proquest_miscellaneous_71296517
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71296517
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ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/sj.npp.1300274