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Vivitrex®, an Injectable, Extended-Release Formulation of Naltrexone, Provides Pharmacokinetic and P...

Vivitrex®, an Injectable, Extended-Release Formulation of Naltrexone, Provides Pharmacokinetic and P...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71296517

Vivitrex®, an Injectable, Extended-Release Formulation of Naltrexone, Provides Pharmacokinetic and Pharmacodynamic Evidence of Efficacy for 1 Month in Rats

About this item

Full title

Vivitrex®, an Injectable, Extended-Release Formulation of Naltrexone, Provides Pharmacokinetic and Pharmacodynamic Evidence of Efficacy for 1 Month in Rats

Publisher

Cham: Springer International Publishing

Journal title

Neuropsychopharmacology (New York, N.Y.), 2003-11, Vol.28 (11), p.1973-1982

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

While oral naltrexone is effective in treating alcohol and opiate dependencies, poor patient adherence and widely fluctuating plasma levels limit its efficacy. To overcome these problems, an extended-release formulation of naltrexone (Vivitrex
®
) was developed by encapsulating naltrexone into injectable, biodegradable polymer microspheres. P...

Alternative Titles

Full title

Vivitrex®, an Injectable, Extended-Release Formulation of Naltrexone, Provides Pharmacokinetic and Pharmacodynamic Evidence of Efficacy for 1 Month in Rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71296517

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71296517

Other Identifiers

ISSN

0893-133X

E-ISSN

1740-634X

DOI

10.1038/sj.npp.1300274

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