P-glycoprotein: from genomics to mechanism
P-glycoprotein: from genomics to mechanism
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Resistance to chemically different natural product anti-cancer drugs (multidrug resistance, or MDR) results from decreased drug accumulation, resulting from expression of one or more ATP-dependent efflux pumps. The first of these to be identified was P-glycoprotein (P-gp), the product of the human
MDR
1 gene, localized to chromosome 7q21. P-g...
Alternative Titles
Full title
P-glycoprotein: from genomics to mechanism
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TN_cdi_proquest_miscellaneous_71304974
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71304974
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1206948
