Loss of collagenase-2 confers increased skin tumor susceptibility to male mice
Loss of collagenase-2 confers increased skin tumor susceptibility to male mice
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Matrix metalloproteinases (MMPs) have fundamental roles in tumor progression
1
,
2
, but most clinical trials with MMP inhibitors have not shown improvements in individuals with cancer
3
. This may be partly because broad-range inhibitors also reduce host-protective antitumor properties of individual MMPs. We generated mice defici...
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Full title
Loss of collagenase-2 confers increased skin tumor susceptibility to male mice
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TN_cdi_proquest_miscellaneous_71333361
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71333361
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng1249
