MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Acute lymphoblastic leukemias carrying a chromosomal translocation involving the mixed-lineage leukemia gene (
MLL
,
ALL1
,
HRX
) have a particularly poor prognosis. Here we show that they have a characteristic, highly distinct gene expression profile that is consistent with an early hematopoietic progenitor expressing select mult...
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Full title
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
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TN_cdi_proquest_miscellaneous_71352524
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71352524
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng765