Mouse Glucocorticoid-Induced Tumor Necrosis Factor Receptor Ligand Is Costimulatory for T Cells
Mouse Glucocorticoid-Induced Tumor Necrosis Factor Receptor Ligand Is Costimulatory for T Cells
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Recently, agonist antibodies to glucocorticoid-induced tumor necrosis factor receptor (GITR) (tumor necrosis factor receptor superfamily 18) have been shown to neutralize the suppressive activity of CD4+CD25+regulatory T cells. It was anticipated that this would be the role of the physiological ligand. We have identified and expressed the gene for...
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Full title
Mouse Glucocorticoid-Induced Tumor Necrosis Factor Receptor Ligand Is Costimulatory for T Cells
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TN_cdi_proquest_miscellaneous_71442982
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71442982
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2334901100
