Adult-Onset Primary Open-Angle Glaucoma Caused by Mutations in Optineurin
Adult-Onset Primary Open-Angle Glaucoma Caused by Mutations in Optineurin
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Publisher
Washington, DC: American Society for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Society for the Advancement of Science
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Scope and Contents
Contents
Primary open-angle glaucoma (POAG) affects 33 million individuals worldwide and is a leading cause of blindness. In a study of 54 families with autosomal dominantly inherited adult-onset POAG, we identified the causative gene on chromosome 10p14 and designated it OPTN (for "optineurin"). Sequence alterations in OPTN were found in 16.7% of families...
Alternative Titles
Full title
Adult-Onset Primary Open-Angle Glaucoma Caused by Mutations in Optineurin
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TN_cdi_proquest_miscellaneous_71452027
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71452027
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1066901
