In Vivo Somatic Cell Gene Transfer of an Engineered Noggin Mutein Prevents BMP4-Induced Heterotopic...
In Vivo Somatic Cell Gene Transfer of an Engineered Noggin Mutein Prevents BMP4-Induced Heterotopic Ossification
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Boston, MA: Copyright by The Journal of Bone and Joint Surgery, Incorporated
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English
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Boston, MA: Copyright by The Journal of Bone and Joint Surgery, Incorporated
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BackgroundThe formation of the skeleton requires inductive signals that are balanced with their antagonists in a highly regulated negative feedback system. Inappropriate or excessive expression of BMPs (bone morphogenetic proteins) or their antagonists results in genetic disorders affecting the skeleton, such as fibrodysplasia ossificans progressiv...
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In Vivo Somatic Cell Gene Transfer of an Engineered Noggin Mutein Prevents BMP4-Induced Heterotopic Ossification
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TN_cdi_proquest_miscellaneous_71455476
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71455476
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ISSN
0021-9355
DOI
10.2106/00004623-200312000-00010
