Tumor antigen–specific induction of transcriptionally targeted retroviral vectors from chimeric immu...
Tumor antigen–specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor–modified T cells
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
High-level systemic delivery of viral vectors to tumors has proved problematic as a result of immune neutralization, nonspecific adhesion, and clearance of circulating viral particles. Some cell types localize to tumors in response to particular biological properties associated with tumor growth. Their use to deliver viral vectors to tumors would a...
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Full title
Tumor antigen–specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor–modified T cells
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TN_cdi_proquest_miscellaneous_71500499
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71500499
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt0302-256