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Tumor antigen–specific induction of transcriptionally targeted retroviral vectors from chimeric immu...

Tumor antigen–specific induction of transcriptionally targeted retroviral vectors from chimeric immu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71500499

Tumor antigen–specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor–modified T cells

About this item

Full title

Tumor antigen–specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor–modified T cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2002-03, Vol.20 (3), p.256-263

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

High-level systemic delivery of viral vectors to tumors has proved problematic as a result of immune neutralization, nonspecific adhesion, and clearance of circulating viral particles. Some cell types localize to tumors in response to particular biological properties associated with tumor growth. Their use to deliver viral vectors to tumors would a...

Alternative Titles

Full title

Tumor antigen–specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor–modified T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71500499

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71500499

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt0302-256

How to access this item