Deficient Smad7 Expression: A Putative Molecular Defect in Scleroderma
Deficient Smad7 Expression: A Putative Molecular Defect in Scleroderma
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Scleroderma is a chronic systemic disease that leads to fibrosis of affected organs. Transforming growth factor (TGF) β has been implicated in the pathogenesis of scleroderma. Smad proteins are signaling transducers downstream from TGF-β receptors. Three families of Smads have been identified: (i) receptor-regulated Smad2 and -3 (R-Smads); (ii) com...
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Full title
Deficient Smad7 Expression: A Putative Molecular Defect in Scleroderma
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TN_cdi_proquest_miscellaneous_71551676
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71551676
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.062010399
