Aquaporin 1 Regulates GTP-Induced Rapid Gating of Water in Secretory Vesicles
Aquaporin 1 Regulates GTP-Induced Rapid Gating of Water in Secretory Vesicles
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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The swelling of secretory vesicles has been implicated in exocytosis, but the underlying mechanism of vesicle swelling remains largely unknown. Zymogen granules (ZGs), the membrane-bound secretory vesicles in exocrine pancreas, swell in response to GTP mediated by a Gα i3protein. Evidence is presented here that the water channel aquaporin-1 (AQP1)...
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Full title
Aquaporin 1 Regulates GTP-Induced Rapid Gating of Water in Secretory Vesicles
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TN_cdi_proquest_miscellaneous_71578846
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71578846
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.072083499
