Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: ident...
Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK(XL) chimeric gene with transforming activity
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Publisher
United States: American Society for Investigative Pathology
Journal title
Language
English
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Publisher
United States: American Society for Investigative Pathology
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Contents
Anaplastic large cell lymphomas are associated with chromosomal aberrations involving the anaplastic lymphoma kinase (ALK) gene at 2p23 that result in the expression of novel chimeric ALK proteins with transforming properties. In most of these tumors, the t(2;5)(p23;q35) generates the NPM-ALK fusion gene. However, several studies have now demonstra...
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Full title
Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK(XL) chimeric gene with transforming activity
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TN_cdi_proquest_miscellaneous_71597206
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71597206
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ISSN
0002-9440
E-ISSN
1525-2191
DOI
10.1016/S0002-9440(10)62574-6
