SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway
SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway
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Full title
SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway
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Publisher
England
Journal title
The EMBO journal, 2004-03, Vol.23 (5), p.1112-1122
Language
English
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Publisher
England
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Scope and Contents
Contents
Protein kinase C-theta (PKCtheta) plays an important role in T-cell activation via stimulation of AP-1 and NF-kappaB. Here we report the isolation of SPAK, a Ste20-related upstream mitogen-activated protein kinase (MAPK), as a PKCtheta-interacting kinase. SPAK interacted with PKCtheta (but not with PKCalpha) via its 99 COOH-terminal residues. TCR/C...
Alternative Titles
Full title
SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway
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Record Identifier
TN_cdi_proquest_miscellaneous_71715313
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71715313
Other Identifiers
ISSN
0261-4189
