Paneth cell trypsin is the processing enzyme for human defensin-5
Paneth cell trypsin is the processing enzyme for human defensin-5
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The antimicrobial peptide human α-defensin 5 (HD5) is expressed in Paneth cells, secretory epithelial cells in the small intestine. Unlike other characterized defensins, HD5 is stored in secretory vesicles as a propeptide. The storage quantities of HD5 are ∼90–450 μg per cm
2
of mucosal surface area, which is sufficient to generate microbicid...
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Full title
Paneth cell trypsin is the processing enzyme for human defensin-5
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TN_cdi_proquest_miscellaneous_71722335
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71722335
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni797
