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Androgens repress Bcl-2 expression via activation of the retinoblastoma (RB) protein in prostate can...

Androgens repress Bcl-2 expression via activation of the retinoblastoma (RB) protein in prostate can...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71733344

Androgens repress Bcl-2 expression via activation of the retinoblastoma (RB) protein in prostate cancer cells

About this item

Full title

Androgens repress Bcl-2 expression via activation of the retinoblastoma (RB) protein in prostate cancer cells

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2004-03, Vol.23 (12), p.2161-2176

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The oncogene
Bcl-2
is upregulated frequently in prostate tumors following androgen ablation therapy, and Bcl-2 overexpression may contribute to the androgen-refractory relapse of the disease. However, the molecular mechanism underlying androgenic regulation of Bcl-2 in prostate cancer cells is understood poorly. In this study, we demonstrated...

Alternative Titles

Full title

Androgens repress Bcl-2 expression via activation of the retinoblastoma (RB) protein in prostate cancer cells

Authors, Artists and Contributors

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Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71733344

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71733344

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1207326

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