Metagenes and Molecular Pattern Discovery Using Matrix Factorization
Metagenes and Molecular Pattern Discovery Using Matrix Factorization
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
We describe here the use of nonnegative matrix factorization (NMF), an algorithm based on decomposition by parts that can reduce the dimension of expression data from thousands of genes to a handful of metagenes. Coupled with a model selection mechanism, adapted to work for any stochastic clustering algorithm, NMF is an efficient method for identif...
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Full title
Metagenes and Molecular Pattern Discovery Using Matrix Factorization
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Author / Creator
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TN_cdi_proquest_miscellaneous_71756093
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71756093
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0308531101
