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LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71781361

LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

About this item

Full title

LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2002-06, Vol.8 (6), p.613-619

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Multiple sclerosis (MS) is a disabling inflammatory demyelinating disease of the central nervous system (CNS) that primarily affects young adults. Available therapies can inhibit the inflammatory component of MS but do not suppress progressive clinical disability. An alternative approach would be to inhibit mechanisms that drive the neuropathology...

Alternative Titles

Full title

LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71781361

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71781361

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm0602-613

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