Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia
Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia
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Author / Creator
TSUCHIYA, T , TAMURA, G , WILSON, K. T , JAMES, S. P , JING YIN , FLEISHER, A. S , TONGTONG ZOU , SILVERBERG, S. G , DEHE KONG , MELTZER, S. J , SATO, K , ENDOH, Y , SAKATA, K , ZHE JIN , MOTOYAMA, T , USUBA, O , KIMURA, W and NISHIZUKA, S
Publisher
Basingstoke: Nature Publishing
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Language
English
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Publisher
Basingstoke: Nature Publishing
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Contents
The adenomatous polyposis coli (APC) tumor suppressor gene is mutationally inactivated in both familial and sporadic forms of colorectal cancers. In addition, hypermethylation of CpG islands in the upstream portion of APC, a potential alternative mechanism of tumor suppressor gene inactivation, has been described in colorectal cancer. Because a sub...
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Full title
Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia
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TN_cdi_proquest_miscellaneous_71785374
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71785374
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1203704
