Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H
Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H
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Chicago, IL: The University of Chicago Press
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Language
English
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Publisher
Chicago, IL: The University of Chicago Press
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The filarial parasite Onchocerca volvulus is the causative agent of river blindness. The adult worms produce microfilariae (mf), which are responsible for the disease pathogenesis; mf activate the complement system, but the activation stops before the formation of terminal complement complexes. Because of the arrest of complement activation, this s...
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Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H
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TN_cdi_proquest_miscellaneous_71860497
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71860497
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ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1086/340649