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Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H

Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71860497

Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H

About this item

Full title

Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H

Publisher

Chicago, IL: The University of Chicago Press

Journal title

The Journal of infectious diseases, 2002-06, Vol.185 (12), p.1786-1793

Language

English

Formats

Publication information

Publisher

Chicago, IL: The University of Chicago Press

More information

Scope and Contents

Contents

The filarial parasite Onchocerca volvulus is the causative agent of river blindness. The adult worms produce microfilariae (mf), which are responsible for the disease pathogenesis; mf activate the complement system, but the activation stops before the formation of terminal complement complexes. Because of the arrest of complement activation, this s...

Alternative Titles

Full title

Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71860497

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71860497

Other Identifiers

ISSN

0022-1899

E-ISSN

1537-6613

DOI

10.1086/340649

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