p73-alpha is capable of inducing scotin and ER stress
p73-alpha is capable of inducing scotin and ER stress
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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p73, like its family member p53, can induce programmed cell death following DNA damage. Here, we report that this mechanism also involves endoplasmic reticulum (ER) stress and the transactivation of scotin, a protein identified recently as a p53 target able to induce ER stress. By using Tet-On inducible cell lines (Saos 2 osteosarcoma cells that la...
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Full title
p73-alpha is capable of inducing scotin and ER stress
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TN_cdi_proquest_miscellaneous_71872779
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71872779
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1207342
