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Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71917192

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

About this item

Full title

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Drug discovery, 2004-05, Vol.3 (5), p.391-400

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
The idea that inhibiting tumour angiogenesis might be an effective anticancer strategy was proposed by Folkman over thirty years ago.
A number of molecules involved in angiogenesis have now been identified, including vascular endothelial growth factor (VEGF), which is an essential regulator of normal and pathological angiogenesis.<...

Alternative Titles

Full title

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71917192

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71917192

Other Identifiers

ISSN

1474-1776

E-ISSN

1474-1784

DOI

10.1038/nrd1381

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