Production of α-1,3-Galactosyltransferase Null Pigs by Means of Nuclear Transfer with Fibroblasts Be...
Production of α-1,3-Galactosyltransferase Null Pigs by Means of Nuclear Transfer with Fibroblasts Bearing Loss of Heterozygosity Mutations
About this item
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Author / Creator
Kolber-Simonds, Donna , Lai, Liangxue , Watt, Steven R. , Denaro, Maria , Arn, Scott , Augenstein, Monica L. , Betthauser, Jeffery , Carter, David B. , Greenstein, Julia L. , Hao, Yanhong , Im, Gi-Sun , Liu, Zhonghua , Mell, Greg D. , Murphy, Clifton N. , Park, Kwang-Wook , Rieke, August , David J. J. Ryan , Sachs, David H. , Forsberg, Erik J. , Prather, Randall S. , Hawley, Robert J. and Jaenisch, Rudolf
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Hyperacute rejection of porcine organs by old world primate recipients is mediated through preformed antibodies against galactosyl-α-1,3-galactose (Galα-1,3-Gal) epitopes expressed on the pig cell surface. Previously, we generated inbred miniature swine with a null allele of the α-1,3-galactosyltransferase locus (GGTA1) by nuclear transfer (NT) wit...
Alternative Titles
Full title
Production of α-1,3-Galactosyltransferase Null Pigs by Means of Nuclear Transfer with Fibroblasts Bearing Loss of Heterozygosity Mutations
Authors, Artists and Contributors
Author / Creator
Lai, Liangxue
Watt, Steven R.
Denaro, Maria
Arn, Scott
Augenstein, Monica L.
Betthauser, Jeffery
Carter, David B.
Greenstein, Julia L.
Hao, Yanhong
Im, Gi-Sun
Liu, Zhonghua
Mell, Greg D.
Murphy, Clifton N.
Park, Kwang-Wook
Rieke, August
David J. J. Ryan
Sachs, David H.
Forsberg, Erik J.
Prather, Randall S.
Hawley, Robert J.
Jaenisch, Rudolf
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_71920587
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71920587
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0307819101
