Loss of tyrosinase activity confers increased skin tumor susceptibility in mice
Loss of tyrosinase activity confers increased skin tumor susceptibility in mice
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The tyrosinase (
Tyr
) gene encodes the enzyme tyrosinase that catalyses the conversion of
L
-tyrosine into DOPA (3,4-dihydroxyphenylalanine)-quinone. The albino mutation abrogates functional activity of tyrosinase resulting in deficiency of melanin pigment production in skin and retina.
Tyr
maps to a region in the central positio...
Alternative Titles
Full title
Loss of tyrosinase activity confers increased skin tumor susceptibility in mice
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TN_cdi_proquest_miscellaneous_71964471
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71964471
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1207565
