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Unimpaired activation of c-Jun NH2-Terminal kinase (JNK) 1 upon CD40 stimulation in B cells of patie...

Unimpaired activation of c-Jun NH2-Terminal kinase (JNK) 1 upon CD40 stimulation in B cells of patie...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71988755

Unimpaired activation of c-Jun NH2-Terminal kinase (JNK) 1 upon CD40 stimulation in B cells of patients with X-linked agammaglobulinemia

About this item

Full title

Unimpaired activation of c-Jun NH2-Terminal kinase (JNK) 1 upon CD40 stimulation in B cells of patients with X-linked agammaglobulinemia

Publisher

New York, NY: Kluwer/Plenum

Journal title

Journal of clinical immunology, 2002-07, Vol.22 (4), p.244-251

Language

English

Formats

Publication information

Publisher

New York, NY: Kluwer/Plenum

More information

Scope and Contents

Contents

X-linked agammaglobulinemia (XLA) is caused by mutations in the gene encoding the cytoplasmic Bruton's tyrosine kinase (Btk). Btk has been shown to play an essential role in the development of B1 (CD5+) and conventional circulating mature B cells (B2) in mouse and man. It has been shown in earlier studies that Btk is involved in both the BCR- and C...

Alternative Titles

Full title

Unimpaired activation of c-Jun NH2-Terminal kinase (JNK) 1 upon CD40 stimulation in B cells of patients with X-linked agammaglobulinemia

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71988755

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71988755

Other Identifiers

ISSN

0271-9142

E-ISSN

1573-2592

DOI

10.1023/A:1016097010274

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