Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarra...
Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays
About this item
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Author / Creator
Grifantini, Renata , Bartolini, Erika , Muzzi, Alessandro , Draghi, Monia , Frigimelica, Elisabetta , Berger, Joel , Ratti, Giulio , Petracca, Roberto , Galli, Giuliano , Agnusdei, Mauro , Monica Giuliani, Marzia , Santini, Laura , Brunelli, Brunella , Tettelin, Hervé , Rappuoli, Rino , Randazzo, Filippo and Grandi, Guido
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
We have used DNA microarrays to follow
Neisseria meningitidis
serogroup B (MenB) gene regulation during interaction with human epithelial cells. Host-cell contact induced changes in the expression of 347 genes, more than 30% of which encode proteins with unknown function. The upregulated genes included transporters of iron, chloride, amino ac...
Alternative Titles
Full title
Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_72047141
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72047141
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt728
