The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expr...
The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit
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Basingstoke: Nature Publishing
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English
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Basingstoke: Nature Publishing
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We previously reported that overexpression of the 24 kDa basic fibroblast factor (or FGF-2) isoform provides protection from the cytotoxic effect of ionizing radiation (IR). DNA double-strand breaks (DSB), the IR-induced lethal lesions, are mainly repaired in human cells by non-homologous end joining system (NHEJ). NHEJ reaction is dependent on the...
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The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit
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TN_cdi_proquest_miscellaneous_72079832
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72079832
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0950-9232
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1476-5594
DOI
10.1038/sj.onc.1205838
