A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology
A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology
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Publisher
Berlin: Springer
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Language
English
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Publication information
Publisher
Berlin: Springer
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Scope and Contents
Contents
Cumulative acquisition of genetic alterations affecting oncogenes or tumor suppressor genes may select for tumor cell clones with enhanced proliferation and survival potential. As a result oxygen and nutrient consumption increases, leading to a tumor microenvironment characterized by low oxygen tension, low glucose levels, and an acidic pH. Hypoxia...
Alternative Titles
Full title
A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_72084998
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72084998
Other Identifiers
ISSN
0946-2716
E-ISSN
1432-1440
DOI
10.1007/s00109-002-0355-1
