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Functional Analysis of the Profilaggrin N-Terminal Peptide: Identification of Domains that Regulate...

Functional Analysis of the Profilaggrin N-Terminal Peptide: Identification of Domains that Regulate...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72089408

Functional Analysis of the Profilaggrin N-Terminal Peptide: Identification of Domains that Regulate Nuclear and Cytoplasmic Distribution

About this item

Full title

Functional Analysis of the Profilaggrin N-Terminal Peptide: Identification of Domains that Regulate Nuclear and Cytoplasmic Distribution

Publisher

Danvers, MA: Elsevier Inc

Journal title

Journal of investigative dermatology, 2002-09, Vol.119 (3), p.661-669

Language

English

Formats

Publication information

Publisher

Danvers, MA: Elsevier Inc

More information

Scope and Contents

Contents

Profilaggrin is expressed in the differentiating granular layer of epidermis and other stratified epithelia, where it forms a major component of cytoplasmic keratohyalin granules. It consists of two distinct domains, an N-terminal S100-like Ca2+- binding domain containing two EF-hands and multiple filaggrin units that aggregate keratin filaments in...

Alternative Titles

Full title

Functional Analysis of the Profilaggrin N-Terminal Peptide: Identification of Domains that Regulate Nuclear and Cytoplasmic Distribution

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_72089408

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72089408

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1046/j.1523-1747.2002.01831.x

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