A futile metabolic cycle activated in adipocytes by antidiabetic agents
A futile metabolic cycle activated in adipocytes by antidiabetic agents
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Thiazolidinediones (TZDs) are effective therapies for type 2 diabetes, which has reached epidemic proportions in industrialized societies. TZD treatment reduces circulating free fatty acids (FFAs), which oppose insulin actions in skeletal muscle and other insulin target tissues. Here we report that TZDs, acting as ligands for the nuclear receptor p...
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Full title
A futile metabolic cycle activated in adipocytes by antidiabetic agents
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TN_cdi_proquest_miscellaneous_72138241
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72138241
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm780
