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The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repo...

The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72140419

The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) mice

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Full title

The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) mice

Author / Creator

Publisher

England

Journal title

Leukemia, 2002-10, Vol.16 (10), p.1992-2003

Language

English

Formats

Publication information

Publisher

England

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Scope and Contents

Contents

Hematopoietic stem cells are identified based on their functional ability to migrate via the blood circulation of transplanted recipients, to home to the host bone marrow and to durably repopulate this organ with high levels of maturing myeloid and lymphoid cells. While a small pool of undifferentiated stem cells with the potential to repeat the en...

Alternative Titles

Full title

The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) mice

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_72140419

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72140419

Other Identifiers

ISSN

0887-6924

DOI

10.1038/sj.leu.2402684

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