Log in to save to my catalogue

Metformin reverses fatty liver disease in obese, leptin-deficient mice

Metformin reverses fatty liver disease in obese, leptin-deficient mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72243203

Metformin reverses fatty liver disease in obese, leptin-deficient mice

About this item

Full title

Metformin reverses fatty liver disease in obese, leptin-deficient mice

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2000-09, Vol.6 (9), p.998-1003

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

There is no known treatment for fatty liver, a ubiquitous cause of chronic liver disease. However, because it is associated with hyperinsulinemia and insulin-resistance, insulin-sensitizing agents might be beneficial. To evaluate this possibility, insulin-resistant ob/ob mice with fatty livers were treated with metformin, an agent that improves hep...

Alternative Titles

Full title

Metformin reverses fatty liver disease in obese, leptin-deficient mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_72243203

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72243203

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/79697

How to access this item