Analysis of ADP-ribose polymer sizes in intact cells
Analysis of ADP-ribose polymer sizes in intact cells
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Author / Creator
Gagné, J P , Shah, R G and Poirier, G G
Publisher
Netherlands: Springer Nature B.V
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Language
English
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Publisher
Netherlands: Springer Nature B.V
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Contents
Poly(ADP-ribose) is a polymer (pADPr) that is synthesized by poly (ADP-ribose) polymerases in response to DNA damaging agents. For instance, chemical alkylating agents such as MNNG or physical stimulation of cells by gamma-rays are well known to induce pADPr synthesis. PARPs are members of a growing family of enzymes which includes PARP-1, PARP-2,...
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Full title
Analysis of ADP-ribose polymer sizes in intact cells
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TN_cdi_proquest_miscellaneous_72244121
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72244121
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ISSN
0300-8177
E-ISSN
1573-4919
DOI
10.1023/A:1011910329010