Clinical importance of interphase cytogenetics detecting occult chromosome lesions in myelodysplasti...
Clinical importance of interphase cytogenetics detecting occult chromosome lesions in myelodysplastic syndromes with normal karyotype
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Author / Creator
Rigolin, GM , Bigoni, R , Milani, R , Cavazzini, F , Roberti, MG , Bardi, A , Agostini, P , Della Porta, M , Tieghi, A , Piva, N , Cuneo, A and Castoldi, G
Publisher
London: Nature Publishing
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Language
English
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Publisher
London: Nature Publishing
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Contents
At diagnosis, approximately half of myelodysplastic (MDS) patients presents a normal karyotype by conventional cytogenetic analysis (CCA). Fluorescent in situ hybridization (FISH) is more sensitive than CCA allowing for the detection of minor clones and of submicroscopic lesions. We have analyzed by FISH 101 MDS patients with normal karyotype for t...
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Full title
Clinical importance of interphase cytogenetics detecting occult chromosome lesions in myelodysplastic syndromes with normal karyotype
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TN_cdi_proquest_miscellaneous_72376891
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72376891
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/sj.leu.2402293
