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Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the st...

Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the st...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72392320

Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway

About this item

Full title

Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway

Publisher

Basingstoke: Nature Publishing

Journal title

Oncogene, 2000-10, Vol.19 (45), p.5173-5181

Language

English

Formats

Publication information

Publisher

Basingstoke: Nature Publishing

More information

Scope and Contents

Contents

Increased expression of fatty acid synthase (FAS) is observed in a clinically aggressive subset of various common cancers and interference with FAS offers promising opportunities for selective chemotherapeutic intervention. The mechanisms by which FAS expression is (up)-regulated in these tumors remain, however, largely unknown. Recently we demonst...

Alternative Titles

Full title

Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_72392320

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72392320

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1203889

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