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Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 σ gene in human hepato...

Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 σ gene in human hepato...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72419763

Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 σ gene in human hepatocellular carcinoma

About this item

Full title

Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 σ gene in human hepatocellular carcinoma

Publisher

Basingstoke: Nature Publishing

Journal title

Oncogene, 2000-11, Vol.19 (46), p.5298-5302

Language

English

Formats

Publication information

Publisher

Basingstoke: Nature Publishing

More information

Scope and Contents

Contents

The 14-3-3 sigma gene has been implicated in G2/M cell cycle arrest by p53. Frequent inactivation of the 14-3-3 sigma gene by hypermethylation of CpG islands has recently been reported in human breast carcinoma. The aim of this study was to examine the methylation status of CpG islands of the 14-3-3 sigma gene in hepatocellular carcinoma (HCC). The...

Alternative Titles

Full title

Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 σ gene in human hepatocellular carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_72419763

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72419763

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1203898

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