Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in hum...
Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine
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Author / Creator
Roy, Michael J , Wu, Mary S , Barr, Lori James , Fuller, James T , Tussey, Lynda G , Speller, Sue , Culp, Jerilyn , Burkholder, Joseph K , Swain, William F , Dixon, Russell M , Widera, Georg , Vessey, Rupert , King, Abbi , Ogg, Graham , Gallimore, Awen , Haynes, Joel R and Heydenburg Fuller, Deborah
Publisher
Oxford: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Oxford: Elsevier Ltd
Subjects
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Scope and Contents
Contents
A DNA vaccine against the hepatitis B virus (HBV) was evaluated for safety and induction of immune responses in 12 healthy, hepatitis-naı̈ve human volunteers using the needle-free PowderJect™ system to deliver gold particles coated with DNA directly into cells of the skin. Three groups of four volunteers received three administrations of DNA encodi...
Alternative Titles
Full title
Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_72471273
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72471273
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/S0264-410X(00)00302-9