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Bruton's Tyrosine Kinase is Activated upon CD40 Stimulation in Human B Lymphocytes

Bruton's Tyrosine Kinase is Activated upon CD40 Stimulation in Human B Lymphocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72684708

Bruton's Tyrosine Kinase is Activated upon CD40 Stimulation in Human B Lymphocytes

About this item

Full title

Bruton's Tyrosine Kinase is Activated upon CD40 Stimulation in Human B Lymphocytes

Publisher

Netherlands: Elsevier GmbH

Journal title

Immunobiology (1979), 2002-10, Vol.206 (4), p.432-440

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier GmbH

More information

Scope and Contents

Contents

Bruton's tyrosine kinase (Btk) is known to be involved in a broad array of signal transduction pathways necessary for the proliferation, survival and development of B cells. Mutations in the Btk gene are causually linked to the development of X-linked agammaglobulinemia (XLA) in humans. We show here, that CD40 ligation leads to tyrosine phosphoryla...

Alternative Titles

Full title

Bruton's Tyrosine Kinase is Activated upon CD40 Stimulation in Human B Lymphocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_72684708

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72684708

Other Identifiers

ISSN

0171-2985

E-ISSN

1878-3279

DOI

10.1078/0171-2985-00192

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